主讲人: 刘国东教授
时间:12月7日上午10:00
地点: 丽湖校区守信楼(原B1栋)420会议室
报告人简介:
刘国东,美国北达科他州立大学(North Dakota State University)化学与生物化学系教授,博士生导师。研究领域主要为基于纳米材料构建的生物传感器、生物分析方法和现场检测装置,应用于生物医药中核酸、蛋白质和外泌体超灵敏检测,食品安全检测,临床即时检测以及环境监测等。在Journal of the American Chemistry Society,Analytical Chemistry, Biosensors and Bioelectronics, Chemical Communications等顶级期刊上发表SCI论文150余篇,被他人正面引用10000余次。获2006和2007年度美国西北太平洋国家实验室杰出工作奖章;2010-2012北达科他州立大学杰出研究奖等。
讲座摘要:
Lateral flow nucleic acid biosensors (LFNAB) have attacked considerable interest due to its short assay time, easy-to-use, low-cost and no requirement of expensive instrumentation. LFNAB-based visual detection of interested targets (DNAs, proteins, pathogen, toxic metals, cells) offer a great point-of-care tool for biomedical and environmental applications. Our research group focus on the development and applications of LFNAB platform with high sensitivity and selectivity. This presentation will introduce the principles of LFNAB, and discuss the design of nucleic acid probes and novel signal amplification strategies with emerging nanomaterials and nucleic acid amplification methods. The applications of LFNABs on the diagnosis of pancreatic cancer and lung cancer will be presented.
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