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张平玉

    职称:特聘副研究员 
    办公电话:26922241  
    Email:p.zhang6@szu.edu.cn

个人简介

张平玉博士,英国皇家科学会‘牛顿学者’,自2010年开始致力于金属配合物及其修饰的复合纳米材料用于肿瘤治疗与诊断的研究2015年荣获英国皇家会牛顿基金资助,在英国华威大学Peter J. Sadler院士课题组担任访问研究员工作2年,从事光活化金属配合物用于耐药菌的光活化治疗和细胞内光催化机理的研究。2017年9月,海外高层次孔雀人才引进深圳大学化学与环境工程学院,开始着手研究靶向多肽修饰的金属配合物和纳米材料用于肿瘤的精准治疗及光催化机理的研究。

目前累计发表SCI论文45,以第一作者或通讯作者发表论文Angew. Chem. Int. Ed.Chem. Sci.BiomaterialsACS Appl. Mater. InterfacesChem. Commun.高水平学术期刊上,论文总引1257次,引用指数H20部分研究成果被高水平杂志和国内外同行科学家的引用和好评申请/授权中国发明专利7。担任Chem. Commun.Dalton Trans. 的审稿人。

工作、教育经历

2018.01-至今: 深圳大学Shenzhen University,化学与环境工程学院,特聘副研究员;

2017/09-2018/01: 深圳大学Shenzhen University,化学与环境工程学院,助理教授;

2015/10-2017/09: 英国华威大学(University of Warwick牛顿高级研究学者Newton Felllow),合作导师:Peter J. Sadler(英国皇家院士和爱丁堡皇家院士);

2010/09-2015/07: 中山大学(Sun Yat-sen University),博士,导师:计亮年院士,巢晖教授

Biography&CV

Pingyu Zhang received her PhD degree from Sun Yat-sen University (2010-2015, Guangzhou, China) in 2015. Since then she was a Newton Fellow funded by Royal Society in the Peter J. Sadler group in the University of Warwick (UK) (2015-2017). She presently (2017- ) is an associate professor in Department of Chemistry and Environmental Engineering, Shenzhen University (Shenzhen, China). Her research focuses on metal-based complexes for anticancer, biosensors, phototherapy application.

主持项目(Funding

1. 国家青年科学基金(National Natural Science Foundation of China (NSFC)217011132018.01-2020.1225万元,主持,在研。

2. 深圳市孔雀人才启动计划项目,2018.12-2021.12270万元,主持,在研。

3. 深圳市科技计划项目-(自由探索)(Science and Technology Foundation of ShenzhenJCYJ20170302144346218)2017.06-2019.0530万元,主持,在研。

4. 英国皇家会牛顿基金(Royal Society Newton International Fund),NF1500122015/09-2017/0999000英镑,主持,结题。

5. 深圳大学新进教师科研启动经费,2018.01-2020.126万元,主持,在研。

研究方向 (Research)

课题组成员(Group Members

代表论文(Publications

1.P. Y. Zhang, H. Huang,* S. Banerjee, G. J. Clarkson, C. Ge, C. Imberti, P. J. Sadler *, Nucleus-Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy. Angew. Chem. Int. Ed., 2019, 58, 2350–2354 (JCR1, IF = 11.9).

2. P. Y. Zhang,‡ Cookson K. C. Chiu,‡ Huaiyi Huang, Yuko PY Lam, Abraha Habtemariam, Thomas Malcomson, Martin J Paterson, Guy J Clarkson, Peter B O'Connor*, Hui Chao*, Peter J Sadler*, Organo-iridium photosensitizers can induce specific oxidative attack on proteins in cancer cells, Angew Chem. Int. Ed., 2017, 56, 14898 (JCR1, VIP Paper, Cover, IF = 11.9).

3. N. A. Smith,‡ P. Y. Zhang,‡ S. E. Greenough, M. D. Horbury, G. J. Clarkson, D. McFeely, A. Habtemariam, L. Salassa, V. G. Stavros, C. G. Dowson*, P. J. Sadler*, Combatting AMR: Photoactivatable ruthenium(II)-isoniazid complex exhibits rapid selective antimycobacterial activity, Chem. Sci., 2017, 8, 395-404 (JCR1, IF = 9.6).

4. P. Y. Zhang,‡ J. Q. Wang,‡ H. Y. Huang, L. N. Ji, H. Chao*, Unexpected high photothemal conversion efficiency of gold nanospheres upon grafting with two-photon luminescent ruthenium(II) complexes: a way towards cancer therapy? Biomaterials, 2015, 63, 102-114 (JCR1, IF = 8.387).

5. P. Y. Zhang,‡ J. Q. Wang,‡ H. Y. Huang, H. M. Chen, R. L. Guan, L. N. Ji*, H. Chao*, Ruthenium(II) complex Coated Gold Nanoparticles as a Two-photon luminescence Probe for Thiols in Live Cells and in Tissues. Biomaterials, 2014, 35, 9003-9011 (JCR1, IF = 8.387).

6. P. Y. Zhang,‡ H. Y. Huang,‡L. N. Ji, H. Chao*, Ruthenium(II) anthraquinone complexes as two-photon luminescent probes for cycling hypoxia imaging in vivo. Biomaterials, 2015, 53, 522-531 (JCR1, IF = 8.387).

7. P. Y. Zhang, H. Y. Huang, J. J. Huang, H. M. Chen, J. Q. Wang, K. Q. Qiu, D. L. Zhao, L. N. Ji, H. Chao*, Non-Covalent Ruthenium(II) Complexes–Single Walled Carbon Nanotube Composites for Bimodal Photothermal and Photodynamic Therapy with Near-Infrared Irradiation, ACS Appl. Mater. Interfaces, 2015, 7, 23278-23290 (JCR1, IF = 7.145).

8. P. Y. Zhang*, Y Wang, K Qiu, Zhiqian Zhao, Rentao Hu, Chuanxin He, Qianling Zhang* and Hui Chao*, NIR phosphorescent osmium (II) complex as lysosome tracking reagent and photodynamic therapeutics. Chem. Commun., 2017, 53, 12341 (JCR1, IF = 6.4).

9. Y. Wang, H. Huang, G. Chen, H. Chen, T. Xu, Q. Tang,Hailiang Zhu*, Qianling Zhang andP. Y. Zhang*, A novel iridium (III) complex for sensitive HSA phosphorescence staining in proteome research, Chem. Commun., 2018, 54, 3282-3285(JCR1, IF = 6.4).

10. Chen Ge, Huaiyi Huang, Yi Wang, Hang Zhao, Pingyu Zhang,* Qianling Zhang,* Near-Infrared Luminescent Osmium(II) Complexes with an Intrinsic RNA-Targeting Capability for Nucleolus Imaging in Living Cells, ACS Applied Bio Materials, 2018, 1, 1587-1593.

More publications are showed in Google Scholar: https://scholar.google.com/citations?user=SswGNBkAAAAJ&hl=zh-CN.

专利成果(Patents)

1. 张平玉,胡仁涛,邱康强,张黔玲一种用于检测组氨酸的荧光探针及制备方法,申请号:2018112783388

2. 张平玉,黄怀义,陈海杰,张黔玲,四核铱配合物及其制备方法与应用,申请号:201810342098.7。  

3. 张平玉,王祎,张黔玲,刘剑洪,一种肝癌靶向型钌配合物及其制备方法与应用申请号:201810224205.6

     获奖荣誉(Awards)

2015年:英国皇家会牛顿学者

2018年:深圳市孔雀人才;

2018年:南山区领航人才

2016年英国皇家化学会会员

2017中国化学会会员

岗位空缺(Available positions

The postdocs and researchers are available now, will support with good salary (more than 280000 RMB per year).

现需招聘博士后/科研人员若干名32万年薪起,同时可享受深圳的人才计划,有意者请发个人简历至p.zhang6@szu.edu.cn

同时欢迎优秀研究生,本科生加入我们团队。