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张平玉

    职称:特聘副研究员 
    办公电话:26922241  
    Email:p.zhang6@szu.edu.cn

 

个人简介

 

张平玉,博士,英国皇家科学会牛顿学者,自2010年开始致力于金属配合物及其修饰的复合纳米材料用于肿瘤治疗与诊断的研究,2015年荣获英国皇家会牛顿基金资助,在英国华威大学Peter J. Sadler院士课题组担任访问研究员工作2年,从事光活化金属配合物用于耐药菌的光活化治疗和细胞内光催化机理的研究。20179月,海外高层次孔雀人才引进深圳大学化学与环境工程学院,开始着手研究靶向多肽修饰的金属配合物和纳米材料用于肿瘤的精准治疗及光催化机理的研究。

 

目前累计发表SCI论文37篇,包括Angew. Chem. Int. Ed.Chem. Sci.BiomaterialsACS Appl. Mater. InterfacesChem. Commun.Chem. Eur. J.等,论文总引860次,引用指数H1022。部分研究成果被Chem. Eur. J. Angew. Chem. Int. Ed.等选为封面论文,并且被高水平杂志Chem. Soc. Rev.和国内外同行科学家的引用和好评。申请中国发明专利5 项。目前为Chem. Commun.Dalton Trans. 的审稿人。

 


工作、教育经历

 

2018.01-至今:深圳大学(Shenzhen University),化学与环境工程学院,特聘副研究员;  

 

2017/09-2018/01深圳大学(Shenzhen University),化学与环境工程学院,助理教授;  

 

2015/10-2017/09英国华威大学(University of Warwick, 牛顿学者(Newton Felllow),合作导师:Peter J. Sadler(英国皇家院士和爱丁堡皇家院士);  

 

2010/09-2015/07中山大学(Sun Yat-sen University),博士,导师:计亮年(中国科学院院士),巢晖教授  

 

 

Biography&CV

 

Pingyu Zhang received her PhD degree from Sun Yat-sen University (2010-2015, Guangzhou, China) in 2015. Since then she was a Newton Fellow funded by Royal Society in the Peter J. Sadler group in the University of Warwick (UK) (2015-2017). She presently (2017- ) is an assistant professor and senior researcher in Department of Chemistry and Environmental Engineering, Shenzhen University (Shenzhen, China). Her research focuses on metal-based complexes for anticancer, biosensors, phototherapy application.

 


主持项目(Funding

 

1.  国家青年科学基金(National Natural Science Foundation of China (NSFC)217011132018.01-2020.1225万元,主持,在研。

 

2.  深圳市科技计划项目-(自由探索)(Science and Technology Foundation of ShenzhenJCYJ20170302144346218)2017.06-2019.0530万元,主持,在研。

 

3.  英国皇家会牛顿基金(Royal Society Newton International Fund),NF1500122015/09-2017/0999000英镑,主持,结题。

 

4.  深圳市孔雀人才启动计划项目,2018.05-2021.12270万元,主持,在研。

 

5.  深圳大学新进教师科研启动经费,2018.01-2020.126万元,主持,在研。

 

 

获奖荣誉(Awards

 

2015  英国皇家会牛顿学者’        

 

2018  深圳市孔雀人才C  

 

 

研究方向 (Research)

课题组成员(Group Members

 

 

 

代表性论文著作(Publications

 

15. Y. Wang, H. Huang, G. Chen, H. Chen, T. Xu, Q. Tang, P. Y. Zhang*, A novel iridium (III) complex for sensitive HSA phosphorescence staining in proteome research. Chemical Communications, 2018, 54(26), 3282-3285(JCR1, IF = 6.4).

 

14. Y. Wang, H. Huang, Q. Zhang, P. Y. Zhang*, Chirality in metal-based anticancer agents. Dalton Transactions, 2018, 47(12), 4017-4026 (JCR1, IF = 4.8).

 

13. P. Y. Zhang, Cookson K. C. Chiu, et al. Organo-iridium photosensitizers can induce specific oxidative attack on proteins in cancer cells, Angew Chem. Int. Ed.,2017, 56, 14898 (JCR1, VIP Paper, Cover, IF = 11.9).

 

12. P. Y. Zhang*, Y Wang, K Qiu, et al. NIR phosphorescent osmium (II) complex as lysosome tracking reagent and photodynamic therapeutics. Chem. Commun., 2017, 53, 12341 (JCR1, IF = 6.4).

 

11.  P. Y. Zhang, Y. Wang, W. X. Huang, et al. “Turn off-on” phosphorescent sensor for biothiols based on a Ru-Cu ensemble, Sensors and Actuators B, 2018, 255, 283-289 (JCR1, IF = 5.6).

 

10.  N. A. Smith,‡ P. Y. Zhang,‡ S. E. Greenough, M. D. Horbury, G. J. Clarkson, D. McFeely, A. Habtemariam, L. Salassa, V. G. Stavros, C. G. Dowson*, P. J. Sadler*, Combatting AMR: Photoactivatable ruthenium(II)-isoniazid complex exhibits rapid selective antimycobacterial activity, Chem. Sci., 2017, 8, 395-404 (JCR1, IF = 9.6).

 

9.  P. Y. Zhang, and P. J. Sadler*. Redox-Active Metal Complexes for Anticancer Therapy. European Journal of Inorganic Chemistry, 2017,1541-1548 (JCR2, IF = 2.9,).

 

8. P. Y. Zhang, and P. J. Sadler*. Advances in the design of organometallic anticancer complexes. Journal of Organometallic Chemistry, 2017, 839, 5-14 (JCR3, IF = 2.7).

 

7.  P. Y. Zhang,‡ J. Q. Wang,‡ H. Y. Huang, K. Q. Qiu, J. J. Huang, L. N. Ji, H. Chao*, Enhancing the Photothermal Stability and Photothermal Efficacy of Gold Nanorods and Nanostars by Coated with Ruthenium(II) Complexes, J. Mater. Chem. B.2017, 5, 671-678 (JCR1, IF = 4.872,).

 

6.  P. Y. Zhang, H. Y. Huang, L. N. Ji, H. Chao, Ruthenium(II) anthraquinone complexes as two-photon luminescent probes for cycling hypoxia imaging in vivo. Biomaterials, 2015, 53, 522-531 (JCR1, IF = 8.387).

 

5.  P. Y. Zhang, J. Q. Wang, H. Y. Huang, L. N. Ji, H. Chao, Unexpected high photothemal conversion efficiency of gold nanospheres upon grafting with two-photon luminescent ruthenium(II) complexes: a way towards cancer therapy? Biomaterials, 2015, 63, 102-114 (JCR1, IF = 8.387).

 

4. P. Y. Zhang, H. Y. Huang, J. J. Huang, H. M. Chen, J. Q. Wang, K. Q. Qiu, D. L. Zhao, L. N. Ji, H. Chao, Non-Covalent Ruthenium(II) Complexes–Single Walled Carbon Nanotube Composites for Bimodal Photothermal and Photodynamic Therapy with Near-Infrared Irradiation, ACS Appl. Mater. Interfaces, 2015, 7, 23278-23290 (JCR1, IF = 7.145).

 

3.  P. Y. Zhang, J. Q. Wang, H. Y. Huang, H. M. Chen, R. L. Guan, L. N. Ji*, H. Chao*, Ruthenium(II) complex Coated Gold Nanoparticles as a Two-photon luminescence Probe for Thiols in Live Cells and in Tissues. Biomaterials, 2014, 35, 9003-9011 (JCR1, IF = 8.387).

 

2.  P. Y. Zhang, L. M. Pei, Y. Chen, W. C. Xu, L. N. Ji, H. Chao*, A dinuclear ruthenium(II) complex as a one- and two-photon luminescent probe for biological Cu2+ detection. Chem. Eur. J., 2013, 19, 15494-15503 (封面, JCR2, IF = 5.771).

 

1.  P. Y. Zhang, J. Q. Wang, H. Y. Huang, L. Qiao, L. N. Ji, H. Chao*, Chiral ruthenium (II) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα. Dalton Trans., 2013, 42, 8907-8917 (JCR2, IF = 4.177).

 

More publications are showed in Google Scholar: https://scholar.google.com/citations?user=SswGNBkAAAAJ&hl=zh-CN.

 

学术会员

 

英国皇家化学会会员

 

中国化学会会员

 

 

岗位空缺(Available positions

 

The postdocs and researchers are available now, will support with good salary (more than 280000 RMB per year).      

 

现需招聘博士后/科研人员若干名(28万年薪起,同时可享受深圳的人才计划),有意者请发个人简历至p.zhang6@szu.edu.cn

 

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