李天任-化环学院

李天任博士，深圳大学化环学院特聘教授，博士生导师，国家级海外高层次人才。2018年于华中师范大学取得有机化学博士学位（美国堪萨斯大学联合培养博士），主要研究方向为有机合成化学与不对称催化反应；2018-2023年于瑞士巴塞尔大学从事博士后研究，研究领域为超分子化学与仿生催化；出站后以高级科学家身份于英国工业界从事制药工艺研发与放大量生产等方向的研究，参与完成多个活性药物的合成与产业化工艺开发；于2025年入选国家自然科学基金优秀青年基金海外项目。拟于2026年5月全职入职深圳大学，任课题组PI，特聘教授。近年来发表论文20余篇，包括Nat. Chem.；J. Am. Chem. Soc.；Nat. Commun.；Angew. Chem. Int. Ed.；JACS Au等，论文获引用2000多次，获授权专利1项。

职位空缺（长期）

研究生

课题组长期招收化学、化学工程专业研究生，欢迎报考深圳大学化学与环境工程学院，并对有机化学，超分子化学，催化化学，药物合成等领域感兴趣的研究生直接联系（可提前1年联系）。联系方式：请发送简历至：chlitr1990@gmail.com；（硕士生请附带本科成绩单，博士生请附带已发表论文或研究总结）。

博士后

课题组长期招收有机合成化学，金属有机化学，光催化，超分子化学等相关背景的博士后研究员，综合年薪33万元以上，深圳市对出站博士后给予36万元生活补助。新政：符合广东省海外博士后人才支持项目，来深从事博士后的，每人最高资助60万元；流动站博士后每人最高资助42万元；其他博士后每人最高资助36万元。

出站博士后可经由深圳大学“荔园留菁”计划考核转为tenure-track教职。

详情请联系：chlitr1990@gmail.com；（可提前1年联系）

助理教授与副研究员

课题组另高薪聘请长聘教轨助理教授1名，专职副研究员1名，有意向加入并协同组建科研团队的青年科研人请单独联系：chlitr1990@

（1）功能化超分子结构的设计及应用；

（2）新型有机化学转化及其在制药工艺中的应用；

(1) Li, T.-R.; Huck, F.; Piccini, G.; Tiefenbacher, K.*, Mimicry of the Proton Wire Mechanism of Enzymes Inside a Supramolecular Capsule Enables β-Selective O-Glycosylations, Nat. Chem. 2022, 14, 985–994.

-Highlighted by Nat. Chem. 2022, 14, 969.

-Highlighted by Synfacts, 2022, 18, 1236;

-Highlighted by Green Synthesis and Catalysis, 2023, 4, 7.

(2) Li, T.-R.; Piccini, G.; Tiefenbacher, K.*, Supramolecular Capsule-catalyzed Highly β-Selective Furanosylation Independent of the SN1/SN2 Pathway. J. Am. Chem. Soc. 2023, 145, 4294-4303.

-Featured on Chem-Station website, spotlight research Sept. 9, 2023.

(3) Li, T.-R.; Das, C.; Piccini, G.; Tiefenbacher, K.*, Tetrafluororesorcin[4]arene Hexameric Capsule Enables the Expansion of the Reactivity Space in Supramolecular Catalysis. J. Am. Chem. Soc. 2025, 147, 11108-11116.

(4) Li, T.-R.; Das, C.; Cornu, I.; Prescimone, A.; Piccini, G.; Tiefenbacher, K.*, Window[1]resorcin[3]arenes: A Novel Macrocycle Able to Self-Assemble to a Catalytically Active Hexameric Cage. JACS Au 2024, 4, 1901-1910.

(5) Hao, X.; Li, T.-R. (co-first author); Chen, H.; Gini, A.; Zhang, X.; Rosset, S.; Mazet, C.; Sakai, N.; Tiefenbacher, K.*; Matile, S.* Bioinspired Ether Cyclizations within a π-Basic Capsules Compared to Autocatalysis on π-Acidic Surfaces and Pnictogen-Bonding Catalysts, Chem.-Eur. J. 2021, 27, 12215-12223.

-Featured in WileyChem, https://mp.weixin.qq.com/s/_l9IB79DMGZzsBesdKKDpw

(6) Li, T.-R.; Tan, F. (co-first author); Lu, L.-Q.*; Wei, Y.; Wang, Y.-N., Yang, Q.-Q.; Chen, J.-R.; Shi, D.-Q.; Xiao, W.-J.* Asymmetric Trapping of Zwitterionic Intermediates by Sulphur Ylides in a Palladium-Catalysed Decarboxylation-Cycloaddition Sequence, Nat. Commun. 2014, 5, 5500.

(7) Li, T.-R.; Cheng, B.-Y.; Zhang, M.-M.; Wang, Y.-N.; Lu, L.-Q.*; Xiao, W.-J. A Cu-Catalyzed Decarboxylative Amination/Hydroamination Sequence: Switchable Synthesis of Functionalized Indoles, Angew. Chem. Int. Ed. 2016, 55, 12422-12426.

-Featured in X-Mol Feb. 11. 2017, https://www.x-mol.com/news/5006.

(8) Li, T.-R.; Zhang, M.-M.; Wang, B.-C.; Lu, L.-Q.*; Xiao, W.-J. Synthesis of 3,3’-Biindoles through a Copper-Catalyzed Friedel–Crafts Propargylation/Hydroamination/Aromatization Sequence. Org. Lett. 2018, 20, 3237-3240.

(9) Li, T.-R.; Maliszewski, M. L. (co-first author); Xiao, W.-J.; Tunge, J. A.* Stereospecific Decarboxylative Benzylation of Enolates: Development and Mechanistic Insight. Org. Lett. 2018, 20, 1730-1734.

(10) Li, T.-R.; Wang, Y.-N.; Lu, L.-Q.*; Xiao, W.-J. Benzoxazinone Derivatives as Transition-Metal-Containing 1,4-Dipolar Precursors in Cyclization Reactions, Tetrahedron Lett. 2018, 59, 1521-1530.

(11) Lu, L.-Q.*; Li, T.-R.; Wang, Q.; Xiao, W.-J.* Beyond Sulfide-Centric Catalysis: Recent Advances in the Catalytic Cyclization Reactions of Sulfur Ylides, Chem. Soc. Rev. 2017, 46, 4135-4149.

(12) Li, T.-R.; Lu, L.-Q.*; Wang, Y.-N.; Wang, B.-C.; Xiao, W.-J.* Divergent Synthesis of Polycyclic Indolines: Copper-Catalyzed Cascade Reactions of Propargylic Carbamates and Indoles, Org. Lett. 2017, 19, 4098-4101.

(13) Li, T.-R.; Cheng, B.-Y.; Fan, S.-Q.; Wang, Y.-N.; Lu, L.-Q.*; Xiao, W.-J. Highly Stereoselective [3+2] Cycloadditions of Chiral Palladium-Containing N1-1,3-Dipoles: A Divergent Approach to Enantio-enriched Spirooxindoles, Chem.-Eur. J. 2016, 22, 6243-6247.

(14) Li, T.-R.; Duan, S.-W.; Ding, W; Liu, Y,-Y; Chen, J.-R.; Lu, L.-Q.*; Xiao, W.-J.* Synthesis of CF3-Containing 3,3’-Cyclopropyl Spirooxindoles by Sequential [3+2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane, J. Org. Chem. 2014, 79, 2296-2302.

-Highlighted by Synfacts 2014, 10, 0459.

(15) Wang, Y.-N.; Li, T.-R. (co-first author); Zhang, M.-M.; Cheng, B.-Y.; Lu, L.-Q.*; Xiao, W.-J.* Formal [3+2] Cycloadditions via Indole Activation: A Route to Pyrroloindolines and Furoindolines, J. Org. Chem. 2016, 81, 10491-10498.

国家自然科学基金优秀青年基金海外项目 (2025)