PI:张平玉 (Pingyu Zhang)
Email: p.zhang6@szu.edu.cn
通讯地址:深圳市南山区学苑大道深圳大学丽湖校区化学与环境工程学院505室
College of Chemistry and Environmental Engineering Room 505, Shenzhen University, Xueyuan Ave, Nanshan, Shenzhen, Guangdong, PR China, 518037
个人简介
张平玉,博士,英国皇家科学会‘牛顿学者’,硕士生导师,自2010年开始致力于金属配合物及其修饰的复合纳米材料用于肿瘤治疗与诊断的研究,2015年荣获英国皇家会牛顿基金资助,在英国华威大学Peter J. Sadler院士课题组担任访问研究员工作2年,从事光活化金属配合物用于耐药菌的光活化治疗和细胞内光催化机理的研究。2017年9月,海外高层次孔雀人才引进深圳大学化学与环境工程学院,开始着手研究金属药物、生物传感、分子影像在肿瘤的治疗与诊断方面的应用。
目前累计发表SCI论文50余篇,以第一作者或通讯作者发表论文于Angew. Chem. Int. Ed.、Chem. Sci.、Biomaterials、ACS Appl. Mater. Interfaces、Chem. Commun.等高水平学术期刊上,论文总引1257次,引用指数H为20,部分研究成果被高水平杂志和国内外同行科学家的引用和好评,申请/授权中国发明专利10余项。主持英国牛顿基金、国家自然科学基金、深圳市科技计划等项目多项。
工作、教育经历
2018.01-至今: 深圳大学(Shenzhen University),化学与环境工程学院,特聘副研究员;
2017/09-2018/01: 深圳大学(Shenzhen University),化学与环境工程学院,助理教授;
2015/10-2017/09: 英国华威大学(University of Warwick),牛顿高级研究学者(Newton Felllow),合作导师:Peter J. Sadler(英国皇家院士和爱丁堡皇家院士);
2010/09-2015/07: 中山大学(Sun Yat-sen University),博士,导师:计亮年院士和巢晖教授
Biography & CV
Pingyu Zhang received her PhD degree from Sun Yat-sen University (2010-2015, Guangzhou, China) in 2015. Since then she was a Newton Fellow funded by Royal Society in the Peter J. Sadler group in the University of Warwick (UK) (2015-2017). She presently (2017- ) is an associate professor in Department of Chemistry and Environmental Engineering, Shenzhen University (Shenzhen, China). Her research focuses on metal-based complexes for anticancer, biosensors, phototherapy application.
主持项目(Funding)
1. 国家自然科学基金-面上项目(NSFC),****7085,2021.01-2024.12,项目负责人,在研。
2. 国家自然科学基金-青年基金(NSFC),****1113,2018.01-2020.12,项目负责人,在研。
3. 深圳市基础研究面上项目(Science and Technology Foundation of Shenzhen,JCYJ20190****001043),2020.05-2022.05,项目负责人,在研。
4. 深圳市基础研究(Science and Technology Foundation of Shenzhen,JCYJ20170****44346218),2017.06-2019.05,项目负责人,结题。
5. 英国皇家会牛顿基金(Royal Society Newton International Fund),NF150012,2015/09-2017/09,项目负责人,结题。
6. 深圳市孔雀人才启动计划项目,2019.01-2021.12,项目负责人,在研。
7. 深圳大学新进教师科研启动经费,2018.01-2021.12,项目负责人,在研。
研究方向(Research)
课题组成员(Group Members)
博士后:梁超、朱佳仪、崔照文
研究生:陆农、罗双玲、欧阳艾、谢嘉恩、赖艺丹、李月、潘志豪、曹凤书
代表论文(Publications)
1. C. Imberti,‡ P. Y. Zhang,‡* H. Y. Huang,* P. J. Sadler,* New Designs for Phototherapeutic Transition Metal Complexes. Angew. Chem. Int. Ed., 2020, 59, 61-73.
2. C. Huang, T. X. Li, J. Y. Liang, H. Y. Huang,* P. Y. Zhang,* Samya Banerjee*, Recent advances in endoplasmic reticulum targeting metal complexes. Coord. Chem. Rev., 2020, 408, 213178 .
3. P. Y. Zhang, H. Y. Huang,* S. Banerjee, G. J. Clarkson, C. Ge, C. Imberti, P. J. Sadler,* Nucleus-Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy. Angew. Chem. Int. Ed., 2019, 58, 2350-2354.
4. P. Y. Zhang,‡ C. K. C. Chiu,‡ H. Y. Huang, Y. P. Y. Lam, A. Habtemariam, T. Malcomson, M. J. Paterson, G. J. Clarkson, P. B O'Connor,* H. Chao,* P. J Sadler,* Organo-iridium photosensitizers can induce specific oxidative attack on proteins in cancer cells, Angew Chem. Int. Ed., 2017, 56, 14898.
5. S. Ye,‡ F. Luo,‡ T. Xu,‡ P. Y. Zhang,* H. Shi, S. Qin, J. Wu, C. He, X. Ouyang, Q. Zhang,* J. Liu,* X. Sun*, Boosting the alkaline hydrogen evolution of Ru nanoclusters anchored on B/N–doped graphene by accelerating water dissociation, Nano Energy, 2019, 104301.
6. Y. Wang, H. Huang, G. Chen, H. Chen, T. Xu, Q. Tang, H. L. Zhu*, Q. L. Zhang and P. Y. Zhang,* A novel iridium (III) complex for sensitive HSA phosphorescence staining in proteome research, Chem. Commun., 2018, 54, 3282-3285.
7. P. Y. Zhang,* Y. Wang, K. Q. Qiu, Z. Q. Zhao, R. T. Hu, C. X. He, Q. L. Zhang,* H. Chao,* A NIR phosphorescent osmium(II) complex as lysosome tracking reagent and photodynamic therapeutics, Chem. Commun., 2017, 53, 12341–12344.
8. C. Ge,‡ J. Y. Zhu,‡ A. Ouyang,‡ N. Lu, Y. Wang, Q. L. Zhang, P. Y. Zhang,* Near-infrared phosphorescent terpyridine osmium(II) photosensitizer complexes for photodynamic and photooxidation therapy, Inorg. Chem. Front., 2020, DOI: 10.1039/d0qi00846j.
9. N. A. Smith,‡ P. Y. Zhang,‡ S. E. Greenough, M. D. Horbury, G. J. Clarkson, D. McFeely, A. Habtemariam, L. Salassa, V. G. Stavros, C. G. Dowson*, P. J. Sadler*, Combatting AMR: Photoactivatable ruthenium(II)-isoniazid complex exhibits rapid selective antimycobacterial activity, Chem. Sci., 2017, 8, 395-404.
10. P. Y. Zhang,‡ J. Q. Wang,‡ H. Y. Huang, L. N. Ji, H. Chao*, Unexpected high photothemal conversion efficiency of gold nanospheres upon grafting with two-photon luminescent ruthenium(II) complexes: a way towards cancer therapy? Biomaterials, 2015, 63, 102-114.
11. P. Y. Zhang,‡ J. Q. Wang,‡ H. Y. Huang, H. M. Chen, R. L. Guan, L. N. Ji*, H. Chao*, Ruthenium(II) complex Coated Gold Nanoparticles as a Two-photon luminescence Probe for Thiols in Live Cells and in Tissues. Biomaterials, 2014, 35, 9003-9011.
12. P. Y. Zhang,‡ H. Y. Huang,‡L. N. Ji, H. Chao*, Ruthenium(II) anthraquinone complexes as two-photon luminescent probes for cycling hypoxia imaging in vivo. Biomaterials, 2015, 53, 522-531.
More publications are showed in Google Scholar: https://scholar.google.com/citations?user=SswGNBkAAAAJ&hl=zh-CN.
获奖荣誉(Awards)
2015年:英国皇家会‘牛顿学者’;
2018年:深圳市孔雀人才;
2018年:南山区领航人才
2016年:英国皇家化学会会员
2017年:中国化学会会员
岗位空缺(Available positions)
现需招聘博士后/科研人员若干名(32万年薪起,同时可享受深圳的人才计划),有意者请发个人简历至p.zha***@szu.edu.cn
The postdocs and researchers are available now, will support with good salary (more than 320000 RMB per year).
同时欢迎优秀研究生、本科生加入我们团队。